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Acetonitrile markets in the US moved higher into mid-March as steady domestic demand from pharmaceutical and laboratory sectors mixed with firmer export interest, narrowing near-term downside risks. Early March buying held volumes steady, while mid-month replenishment from Asia and South America supported confidence. Rising freight and feedstock costs trimmed margins, though Gulf Coast supply remained uninterrupted, keeping the market broadly balanced between ample co-product output and buyers rebuilding inventories ahead of spring activity. Sectoral demand patterns shaped pricing: domestic pharma and lab demand for synthesis and specialty intermediates remained a stable base for spot and contract flows; industrial grade demand softened for some manufacturers amid tariff-driven sourcing disruptions. Export demand remained firm, supporting sentiment for pharma grade. Upstream dynamics, including feedstock cost increases, pressured margins. By the week ending mid-March, the market showed a clear uptrend, while the near-term outlook remains mixed with potential for modest declines and gains as spring restocking proceeds. Monitor feedstock, freight, and export inquiry trends.